科研成果

Divergent Entry to Walsucochin Nortriterpenoids: Total Syntheses of (±)-Walsucochin A and (±)-Walsucochinoids C?F

作者:  來源:  發(fā)布日期:2021-05-14  瀏覽次數(shù):

論文信息:Divergent Entry to Walsucochin Nortriterpenoids: Total Syntheses of (±)-Walsucochin A and (±)-Walsucochinoids C?F,Danyang Zhang, Dan Xu, Xinyue Chen, Huan Zhou, and Gong Xu*  The Journal of Organic Chemistry ,2021,https://doi.org/10.1021/acs.joc.1c00401

JCR分區(qū)Q1,中科院大類2區(qū)【TOP】, IF=4.335

論文摘要: Nortriterpenoids isolated from Walsura cochinchinensis have attracted much attention from both synthetic and medicinal chemists, yet only recently have efficient synthetic approaches to any members appeared. Shown here is that the commonintermediate with a 6/6/5/6-fused tetracyclic ring nucleus can be converted to walsucochin family members. The first total syntheses of (±)-walsucochin A, (±)-walsucochinoids C?F, and their analogues were achieved in this work.

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