Dr. Dun Wang

 

　　Professor in Department of Entomology

　　Email: wanghande@yahoo.com; wanghande@nwsuaf.edu.cn

　　Tel: +86-29-87091511

 

 

 

 

 

　　Research interests

　　1. Insect pathogens and related microorganisms: The functional genomics of the Baculoviruses, such as HearNPV CypoGV and OrerNPV. Based on the results of functional genomics on NPVs, we produce the genetic modified nucleopolyhedrovirus to improve biocontrol for insect pests. Another important point is the interaction between baculoviruse and its insect host, especially for the larvae behavior regulation induced by viral infection. Besides this, our lab team also focused on other pathogens against insects, including Beauveria, Codyceps and Bacillus for biocontrol and diversity.

　　2. Pharmacological analyses and utilization of bioactive compounds from traditional Chinese herbal insects. The natural compounds from herbal insects have a prospective potential on cancer treatment and health improvement drug development based on our previous study. We are focusing on the molecular and cellular pharmacology of these compounds and isolation of new compounds from insect herbals.

　　Recent publications

　　[1] Yu, H., Zhou, B., Meng, J., Xu, J., Liu, T.-X., Wang D.*. Recombinant Helicoverpa armigera nucleopolyhedrovirus with arthropod-specific neurotoxin gene RjAa17f from Rhopalurus junceus enhances the virulence against the host larvae. Insect Science. 2015, doi:10.1111/1744-7917.12289（SCI）

　　[2] Huan Yu, Jian Xu,, Qiang Liu,Tong-Xian Liu, Dun Wang* . Ha83, a Chitin Binding Domain Encoding Gene, Is Important to Helicoverpa armigera Nucleopolyhedrovirus Budded Virus Production and Occlusion Body Assembling. Scientific Reports, 2015, 5（NO: 11088）， doi:10.1038/srep11088（SCI）

　　[3] Huan Yu, Jiao Meng, Jian Xu, Tongxian Liu, Dun Wang* . A novel neurotoxin gene ar1b recombination enhances the efficiency of Helicoverpa armigera nucleopolyhedrovirus as a pesticide by inhibiting the host larvae ability to feed and grow. PLOS ONE, 2015, 10（8）： e0135279. （SCI）

　　[4] W.P. Wu, J. Cao, J.Y. Wu, H. Chen and D. Wang*. Anticancer activity of Bombyx batryticatus ethanol extract against the human tumor cell line HeLa. Genetics and Molecular Research, 2015, 14 （1）： 79 - 88 （SCI）

　　Graduate students who participate in international conferences and academic reports

　　1. Yu Huan （PhD student）。 Ha83, a chitin binding domain encoding gene, is important to Helicoverpa armigera nucleopolyhedrovirus budded virus production and occlusion body assembling.The 5th International Symposium on Insect Physiology, Biochemistry and Molecular Biology. （Guangzhou, 2015）

　　2. Fan Jiangbin （PhD student）。 Study the relationship between the genetic expression and virulence of CpGV-M and CpGV-ZY through RNA-seq and q-PCR.The 5th International Symposium on Insect Physiology, Biochemistry and Molecular Biology.  （Guangzhou, 2015）

　　Graduate student academic awards

　　Dr. Yu Huan is granted for PhD national scholarship in 2015, etc.

　　Graduate employment

　　In addition to study abroad, the graduated students were all employed in jobs （or post-doctoral）。